网站地图 | 联系我们 | 管理系统 | 登录邮箱 | 内网办公 | English | 中国科学院    
首页 所况介绍 机构设置 科研成果 研究队伍 合作交流 研究生教育 党群园地 科学传播
 
 首页 >>>  研究队伍 >>>  植物所人才
 

麻密


职务/职称: 研究员
联系电话: (86)-010-62836255
电子邮件: mami@ibcas.ac.cn
个人网页: http://klpr.ibcas.ac.cn/news/98
课 题 组: 植物对重金属胁迫应答及生物修复研究组

麻密,女,博士,研究员,博士生导师。

19618月生,1983年和1986年在北京大学分别获学士和硕士学位,1994年在中科院植物所获博士学位。1995年至1996年在香港科技大学做博士后,1996年至1997年为香港科技大学访问学者,1998年至2000年在香港城市大学做访问研究员。现任中国科学院植物研究所研究员,中国科学院研究生院教授,兼任中国植物生理与分子生物学学会植物修复生物学专业委员会委员,中国植物学会植物结构与生殖生物学专业委员会委员,北京植物学会理事,《植物学报》、《应用与环境生物学》和《生命世界》编委。迄今发表论文50余篇,其中第一作者和通讯作者论文40余篇,SCI收录刊物论文20余篇。已培养博士14名硕士5名;正在指导博士生和硕士生4名。

主要研究工作:

利用分子生物学技术,结合遗传学、细胞生物学和蛋白质组学等方法研究植物对重金属污染修复的分子基础及生物技术,重金属对植物毒害的分子机理,培育重金属低积累安全作物新种质。从特殊生境植物如超富集砷的凤尾蕨属(Pteris)和超富集镉的景天属(Sedum)植物以及大量拟南芥突变体中克隆了重金属转运蛋白基因、结合蛋白基因和重金属解毒相关基因,并对其功能进行了分析;发现部分重金属(如镉等)通过内质网应激途径诱发植物细胞程序性死亡的毒害机理;利用分子调控技术抑制水稻种子中镉的积累,对修复重金属污染环境和发展安全农作物进行了新的探索。

主持和参加的科研项目:

[1]“基于蜈蚣草FOX-Hunting系统的砷积累相关基因的挖掘和功能分析”,国家自然科学基金(2014.1-2017.12),主持人。 

[2]“北方稻区水稻镉污染现状及分子模块解析-II”,中国科学院先导性专项子任务(2013.8-2017.12),负责人。 

[3]“我国主产区大豆重金属污染调查”,国家科技基础性工作专项课题(2015.1-2019.12),负责人。 

[4]“内质网应激参与镉诱发的植物细胞程序性死亡的机制研究”,国家自然科学基金(2012.1-2015.12),主持人。  

[5]“污泥土地处置重金属污染土壤生物修复机制与技术”,中国科学院知识创新工程重要方向性项目子课题(2009.1-2011.12),主持人。 

[6]“转基因植物目标核酸与蛋白的SPR检测技术”,国家转基因生物新品种培育重大专项课题转基因生物安全监测技术子课题(2008.7-2011.4),主持人。 

研究论文(注*为通讯作者):

Xi HM, Xu H, Xu WX, He ZY, Xu WZ*, Ma M*. 2016. A SAL1 loss-of-function Arabidopsis mutant exhibits enhanced cadmium tolerance in association with alleviation of endoplasmic reticulum stress. Plant & Cell Physiology, 57 (6): 1210-1219. 

He ZY, Yan HL, Chen YS, Shen HL, Xu WX, Zhang HY, Shi L, Zhu YG*, Ma M*. 2016. An aquaporin PvTIP4; 1 from Pteris vittata may mediate arsenite uptake. New Phytologist, 209: 746-761. 

Sun YY, Xu WZ, Wu L, Wang RZ, He ZY, Ma M*. 2016. An Arabidopsis mutant of inositol pentakisphosphate 2-kinase AtIPK1 displays reduced arsenate tolerance. Plant, Cell & Environment, 39: 416-426. 

Yu PL, Yuan JH, Zhang H, Deng X, Ma M, Zhang HY *. 2016. Engineering metal-binding sites of bacterial CusF to enhance Zn/Cd accumulation and resistance by subcellular targeting. Journal of Hazardous Materials, 302: 275-285. 

Xu WZ, Dai WT, Yan HL, Li S, Shen HL, Chen YS, Xu H, Sun YY, He ZY, Ma M*. 2015. Arabidopsis NIP3;1 plays an important role in arsenic uptake and root-to-shoot translocation under arsenite stress conditions. Molecular Plant, 8: 722-733 

Shen HL, He ZY*, Yan HL, Xing ZN, Chen YS, Xu WX, Xu WZ, Ma M. 2014. The fronds tonoplast quantitative proteomic analysis in arsenic hyperaccumulator Pteris vittata L. Journal of Proteomics, 105:46-57 

Yu PL, Yuan JH, Deng X, Ma M, Zhang HY*. 2014. Subcellular targeting of bacterial CusF enhances Cu accumulation and alters root to shoot Cu translocation in Arabidopsis. Plant Cell Physiology, 55: 1568-1581 

Xu H, Xu WZ, Xi HM, Ma WW, He ZY, Ma M*. 2013. The ER luminal binding protein (BiP) alleviates Cd2+-induced programmed cell death through endoplasmic reticulum stresscell death signaling pathway in tobacco cells. Journal of Plant Physiology, 170: 1434-1441 

Dai WT, Yang XX, Chen H, Xu WZ, He ZY, Ma M*. 2013. Phytotoxicities of inorganic arsenic and dimethylarsinic acid to Arabidopsis thaliana and Pteris vittata. Bulletin of Environmental Contamination and Toxicology, 91: 652-655 

Chen YS, Xu WZ, Shen HL, Yan HL, Xu WX, He ZY, Ma M*. 2013.Engineering arsenic tolerance and hyperaccumulation in plants for phytoremediation by a PvACR3 transgenic approach. Environmental Science & Technology. 47(16), 9355–9362

Zhao ZY, Chen YS, Xu WZ*, Ma M. 2013. Surface plasmon resonance detection of transgenic Cry1Ac cotton (Gossypium spp.). Journal of Agricultural and Food Chemistry, 61: 2964-2969

Guo JB, Xu WZ, Ma M*. 2012. The assembly of metals chelation by thiols and vacuolar compartmentalization conferred increased tolerance to and accumulation of cadmium and arsenic in transgenic Arabidopsis thaliana. Journal of Hazardous Materials, 199-200: 309-313

Ma WW, Xu WZ, Xu H, Chen YS, He ZY, Ma M*. 2010. Nitric oxide modulates cadmium influx during cadmium-induced programmed cell death in tobacco BY-2 suspension cultures. Planta, 232: 325-335

Teng Y, Xu WZ*, Ma M. 2010. cGMP is required for seed germination in Arabidopsis thaliana. Journal of Plant Physiology, 167:885-889

Yang XX, Chen H, Dai XJ, Xu WZ, He ZY, Ma M*. 2009. Evidence of vacuolar compartmentalization of arsenic in the hyperaccumulator Pteris vittata. Chinese Science Bulletin, 54: 4229-4233

Guo JB, Dai XJ, Xu WZ, Ma M*. 2008. Overexpressing GSH1 and AsPCS1 simultaneously increases the tolerance and accumulation of cadmium and arsenic in Arabidopsis thaliana. Chemosphere, 72: 1020-1026

Zheng YQ, Dai XJ, Wang L, Xu WZ, He ZY, Ma M*. 2008. Arsenate reduces copper phytotoxicity in gametophytes of Pteris vittata. Journal of Plant Physiology, 165:1906-1916

Zheng YQ, Xu WZ, He ZY, Ma M*. 2008. Plant regeneration of the arsenic hyperaccumulator Pteris vittata L. from spores and identification of its tolerance and accumulation of arsenic and copper. Acta Physiologiae Plantarum, 30: 249-255

Yang XX, Chen H, Xu WZ, He ZY, Ma M*. 2007. Hyperaccumulation of arsenic by callus, sporophytes and gametophytes of Pteris vittata cultured in vitro. Plant Cell Reports, 26: 1889-1897

Li JC, Guo JB, Xu WZ, Ma M*. 2007. RNAi-mediated silencing of phytochelatin synthase gene reduce cadmium accumulation in rice seeds. Journal of Integrative Plant Biology, 49: 1032–1037

Zhang HY, Xu WZ, Dai WT, He ZY, Ma M*. 2006. Functional characterization of cadmium-responsive garlic gene AsMT2b: A new member of metallothionein family. Chinese Science Bulletin, 51: 409-416

Li JC, Guo JB, Xu WZ, Ma M*. 2006. Enhanced cadmium accumulation in transgenic tobacco expressing the phytochelatin synthase gene of Cynodon dactylon. Journal of Integrative Plant Biology, 48: 928-937

He ZY, Li JC, Zhang HY, Ma M*. 2005. Different effects of calcium and lanthanum on the expression of phytochelatin synthase gene and cadmium absorption in Lactuca sativa. Plant Science, 168: 309-318

Zhang HY, Jiang YN, He ZY, Ma M*. 2005. Cadmium tolerance and antioxidative responses of the garlic plant. Journal of Plant Physiology, 162: 977-984

Zhang HY, Xu WZ, Guo JB, He ZY, Ma M*. 2005. Coordinated responses of phytochelatins and metallothioneins to heavy metals in garlic seedlings. Plant Science, 169: 1059-1065

Ma M, Lau PS, Jia YT, Tsang WK, Lam SKS, Tam NFY, Wong YS*. 2003. The isolation and characterization of Type 1 metallothionein (MT) cDNA from a heavy-metal tolerant plant, Festuca rubra cv. Merlin. Plant Science, 164:51-60

Geng S, Ma M*, Li GF F, Ye HC. 2002. Anther-specific expression of ipt gene in transgenic tobacco and its effect on plant development. Transgenic Research,11: 269-278

Geng S, Ma M, Ye HC*, Liu BY, Li GF, Chong K. 2001. Effects of ipt gene expression on the physiological and biochemical characteristics of Artemisia annua L. Plant Science, 160: 691-698

国家发明专利:

[1] 麻密,姜瑛楠,冯保民,李江川,杨树德. 一种新的大蒜重金属抗性相关基因及其应用:中国,ZL02131036X.

[2] 麻密,李江川,王剑虹,朱至清,屈贵平. 一种培育转基因小麦的方法及其应用:中国,ZL03153280.2.

[3] 麻密,何振艳,李江川,张海燕. 一种降低镉在植物中积累的方法及其应用:中国,ZL03157196.6.

[4] 麻密,何振艳,徐文忠,杨学习. 一种蜈蚣草ABC转运蛋白及其编码基因与应用:中国,ZL200410080857.5.

[5] 麻密,李江川,郭江波,徐文忠,何振艳. 一种培育低重金属积累植物的方法:中国,ZL200410096858.9.

[6] 麻密,戴晓静,郑永强,徐文忠,何振艳. 一种蜈蚣草经绿色球状体再生植株的方法及其专用培养基:中国,ZL200810239942.X.

[7] 徐文忠,麻密,戴晓静,孙洋洋,何振艳. 一种与砷响应相关的调控片段及其应用. ZL201010128600.8.

[8] 何振艳,麻密,徐文忠,陈宏林. 一种植物砷抗性相关的蛋白及编码基因及其应用:中国,ZL201010116397.2.


[ 打印本页 ]   [ 关闭窗口 ]    

| 本站导航 | 园区风光| 联系我们 |
版权所有:中国科学院植物研究所 地址:北京市海淀区香山南辛村20号 邮编:100093 电话:010-62590835
网站备案号:京ICP备05002828号       文保网安备案号:1101080078