姓  名: 杨文强
职务/职称: 研究员
联系电话: 010-62836945
电子邮件: wqyang@ibcas.ac.cn
个人网页: http://www.klpbcas.com/yjdw/ktzz/ywq/
课 题 组: 光合作用代谢调控机制研究组
杨文强,男,博士,研究员,博士生导师。

2000年和2003年在东北农业大学分别获学士和硕士学位,2008年在中国科学院遗传与发育生物学研究所获博士学位。20092月至20171月在美国斯坦福卡内基研究所植物生物学系从事博士后研究和研究助理工作。期间于20093月至5月在美国科罗拉多再生能源国家实验室(NREL)访问研究。20172月到中国科学院植物研究所工作。

主要研究方向:

光合作用是世界上最重要的化学反应(1988年诺贝尔奖颁奖词),与人类生存息息相关。实验室致力于光合作用代谢调控机制研究。以衣藻和大豆等豆科植物为研究对象,运用遗传学、生理学、细胞学、分子生物学、生物化学、生物物理学和组学等多学科的理论与技术,挖掘关键因子、揭示分子机理,更好的理解光合作用调控机制,为农业科技发展提供理论指导和技术支持。研究方向包括:

1光合作用新的调控机制。

衣藻基因组测序发现597个在光合生物中有同源,而非光合生物中不存在的蛋白,这些蛋白被命名为GreenCut,且绝大部分蛋白的功能是未知的。试图剖析这些蛋白可能在光合作用过程中发挥新的不为所知的功能。

2光合作用与碳代谢互作网络。

光合作用形成的磷酸丙糖的去向直接决定了有机碳的分配,系统的研究这些参与碳代谢网络中酶类,如淀粉酶、磷酸果糖激酶与光合作用的相互作用机制,试图探讨光合作用和这些重要碳代谢网络的互作关系。

3叶绿体蛋白转运与蛋白质量控制。

叶绿体是光合作用发生的场所,同时也是重要的生物反应器合成脂质、氨基酸等物质;传递逆向信号、调节细胞内能量和氧化还原平衡;叶绿体还参与了植物的激素合成、抗病、免疫以及环境适应等。叶绿体诸多功能的行使离不开蛋白质的参与。研究物种在长期进化过程中,叶绿体蛋白转运和蛋白质量控制的交流协作如何维持叶绿体的功能、调控叶绿体的发育以及理解叶绿体与其它细胞器蛋白质量控制网络的互作等、具有非常重要的意义。

4大豆等豆科植物光合作用高光效机理。

大豆是一种重要的粮食作物,几乎存在于人类饮食的方方面面,对人类生活具有重要的意义。但目前大豆光合作用光能高效利用存在瓶颈、亟待建立高效光合作用新体系,通过筛选大豆高光效材料,鉴定大豆高光效的遗传调控因子,解析高光效的分子调控机理,获得可用于作物高光效的分子调控网络,为实现大豆的高产提供理论支持。

研究论文(*标记为通讯作者)

Peer Reviewed Articles

2021

Wenfeng Tu, Lishuan Wu, Chunyan Zhang, Ruixue Sun, Liangsheng Wang, Wenqiang Yang, Chunhong Yang and Cheng Liu. 2021, Neoxanthin affects the stability of the C2S2M2-type photosystem II supercomplexes and the kinetics of state transition in Arabidopsis. Plant J, 104(6): 1724-1735.

2020

杨文强*,郭梦曦.2020.藻类与光合作用.生命世界. 2: 30-31

2019

Zhiyun Li, Weiping Mo; Liqiang Jia, Yong-Chao Xu, Weijiang Tang, Wenqiang Yang, Ya-Long Guo, Rongcheng Lin, 2019.  Rice FLUORESCENT1 Is Involved in the regulation of chlorophyll. Plant Cell Physiol, 60(10): 2307-2318.

Jin Liu, Zheng Sun, Xuemei Mao, Gerken Henri, Xiaofei Wang, Wenqiang Yang. 2019. Multiomics analysis reveals a distinct mechanism of oleaginousness in the emerging model alga Chromochloris zofingiensis. Plant J, doi: 10.1111/tpj.14302.

Yue Wang, Huanling Yang, Xinna Zhang, Fei Han, Wenfeng Tu and Wenqiang Yang. 2019. Microalgal hydrogen production. Small Methods, 4: 1900514.

2018

Wittkopp TM, Saroussi S, Yang W, Johnson X, Kim RG, Heinnickel ML, Russell JJ, Phuthong W, Dent RM, Broeckling CD, Peers G, Lohr M, Wollman FA, Niyogi KK, Grossman AR*. 2018. GreenCut protein CPLD49 of Chlamydomonas reinhardtii associates with thylakoid membranes and is required for cytochrome b6f complex accumulation. Plant J., 94: 1023-1037.

涂文凤, 王月, 杨文强*. 2018. 基因编辑技术在莱茵衣藻中的应用进展. 生命科学, 30: 987-993.

2016

 Mark Heinnickel, Rick Kim, Tyler M Wittkopp, Wenqiang Yang, Karim Walters, Stephen Herbert, Arthur R Grossman. 2016. Tetratricopeptide repeat protein protects photosystem I from oxidative disruption during assembly. PNAS. 113(10): 2774-2779

2015

Wenqiang Yang*,# , Tyler M Wittkopp#, Xiaobo Li, Jaruswan Warakanont, Alexandra Dubini, Rick Kim, Claudia Catalanotti, Eva C M Nowack, Munevver Aksoy, Sarah D’Adamo, Luke Mackinder, Dudley Page, Mark Heinnickel, Xenie Johnson, Jean Alric, Martin C Jonikas, Christoph Benning, Sabeeha Merchant, Matthew C Posewitz, Arthur R Grossman. 2015. Critical role of Chlamydomonas reinhardtii ferredoxin-5 in maintaining membrane structure and dark metabolism. PNAS. 112(48): 14978-14983 (#Equal Contribution)

Wenqiang Yang*, Claudia Catalanotti, Sarah D’Adamo, Tyler M Wittkopp, Cheryl J Ingram-Smith, Luke Mackinder, Tarryn Miller, Adam L. Heuberger, Graham Peers, Kerry S Smith, Martin C Jonikas, Arthur R Grossman, Matthew C Posewitz. 2015. Alternative Acetate Production Pathways in Chlamydomonas reinhardtii during Dark Anoxia and the Dominant Role of Chloroplasts in Fermentative Acetate Production. The Plant Cell. 26(11):4499-4518

2013

Deqiang Duanmu, Nathan C Rockwell, Rachel M Dent, Krishna Niyogi, Wenqiang Yang, Arthur R Grossman, Clark Lagarias. 2013. Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival. PNAS.110(9):3621-3626

 Mark Heinnickel ML, Jean Alric, Tyler M Wittkopp, Wenqiang Yang, Claudia Catalanotti, Rachel Dent, Krishina Niyogi, Francis-Andrew Wollman, Arthur R Grossman. 2013. Novel Thylakoid Membrane GreenCut Protein CPLD38 Impacts Accumulation of the Cytochrome b6f Complex and Associated Regulatory Processes. J Biol Chem. 288(10):7024-7036

2012

Claudia Catalanotti, Alexandra Dubini, Venkataramanan Subramanian, Wenqiang Yang, Leonardo Magneschi, Florence Mus, Michael Seibert, Matthew C Posewitz, Arthur R Grossman. 2012. Altered Fermentative Metabolism in Chlamydomonas reinhardtii Mutants Lacking Pyruvate Formate Lyase and both Pyruvate Formate Lyase and Alcohol Dehydrogenase. The Plant Cell. 24:692-707

Leonardo Magneschi, Claudia Catalanotti, Alexandra Dubini, Wenqiang Yang, Matthew C Posewitz, Michael Seibert, Pierdomenico Perata, Arthur R Grossman. 2012. A Mutant in the ADH1 Gene of Chlamydomonas reinhardtii Elicits Metabolic Restructuring during Anaerobiosis. Plant Physiology.158(3):1293-1305

2011

 Jonathan E. Meuser, Sarah D’Adamo, Robert E Jinkerson, Florence Mus, Wenqiang Yang, Maria L Ghirardi, Michael Seibert, Arthur R Grossman, Matthew CPosewitz. 2011. Genetic Disruption of both Chlamydomonas reinhardtii [FeFe]-Hydrogenases: Insight into the Role of HYDA2 in H2 Production. Biochem Biophys Res Commun. 417(2):704-709

David Gonzalez-Ballester, Wirulda Pootakham, Florence Mus, Wenqiang Yang, Claudia Catalanotti, Leonardo Magneschi, Jose J. Higuera, Amaury de Montaigu, Matthew Prior, Aurora Galván, Emilio Fernandez, Arthur R Grossman. 2011. Reverse Genetics in Chlamydomonas: A Moderate Throughput Platform for Isolating Insertional Mutants. Plant Methods.7:24. doi:10.1186/1746-4811-7-24

Wenying Xu, Rendong Yang, Meina Li, Zhuo Xing, Wenqiang Yang, Guang Chen, Han Guo, Xiaojie Gong, Zhou Du, Zhenhai Zhang, Xingming Hu, Dong Wang, Qian Qian, Tai Wang, Zhen Su, Yongbiao Xue. 2011. Transcriptome Phase Distribution Analysis Reveals Diurnal Regulated Biological Processes and Key Pathways in Rice Flag Leaves and Seedling Leaves. PLoS One. 6(3): e17613

2010及以前

Wenqiang Yang, Ying Lai, Meina Li,Wenying Xu,YongbiaoXue. 2008. A Novel C2-domain-Containing Phospholipid Binding Protein, OsPBP1, Is Involved in Pollen Fertility in Rice (Oryza sativa L.). Molecular Plant. 1: 770-785

Wenqiang Yang, Zhaosheng Kong,Edith Omo-Ikerodah, Wenying Xu,Yongbiao Xue. 2008. A Calcineurin B-Like Interacting Protein Kinase OsCIPK23 Functions in Pollination and Drought Stress Responses in Rice. Journal of Genetics and Genomics. 35:531-543

Meina Li, Wenying Xu, Wenqiang Yang, Zhaosheng Kong,Yongbiao Xue. 2007. Genome-Wide Gene Expression Profiling Reveals Conserved and Novel Molecular Functions of the Stigma in Rice (Oryza sativa L.). Plant Physiology.144:1797-1812

 Zhaosheng Kong, Meina Li, Wenqiang Yang, Wenying Xu,Yongbiao Xue. 2006. A Novel Nuclear-Localized CCCH-type Zinc Finger Protein, OsDOS, Is Involved in Delaying Leaf Senescence in Rice (Oryza sativa L.). Plant Physiology. 141: 1376–1388

Reviews and Book Chapters

Tyler M Wittkopp, Shai Saroussi, Wenqiang Yang, Arthur R Grossman. 2015. Chapter 11: The GreenCut - a tool for understanding the functions and relationships of proteins conserved in green lineage organisms. Horizon: Chloroplasts: Current Research and Applications

Wenqiang Yang*, Claudia Catalanotti, Tyler M Wittkopp Matthew C Posewitz, Arthur R Grossman. (2014). Algae after dark: mechanisms to cope with anoxic/hypoxic conditions. Coming of age of Chlamydomonas as a model alga. Plant Journal 82(3):481-503

Wenqiang Yang*, Claudia Catalanotti, Matthew C Posewitz, Jean Alric, Arthur R Grossman. 2014. Insight into Algal Fermentation Metabolism. Springer: Low Oxygen Stress in Plants.

Claudia Catalanotti, Wenqiang Yang, Matthew C Posewitz, Arthur R Grossman. 2013. Fermentation metabolism and its evolution in algae. Frontiers in Plant Science. doi: 10.3389/fpls.2013.00150

Arthur R Grossman, Claudia Catalanotti, Wenqiang Yang, Alexandra Dubini, Leonardo Magneschi, Venkataramanan Subramanian, Matthew C Posewitz, Michael Seibert. 2011. Multiple Facets of Anoxic Metabolism and Hydrogen Production in the Unicellular Green Alga Chlamydomonas reinhardtii. New Phytologist. 190(2): 279-88