姓  名: 杨文强
职务/职称: 研究员
联系电话: 010-62836945
电子邮件: wqyang@ibcas.ac.cn
个人网页: http://www.klpbcas.com/yjdw/ktzz/ywq/
课 题 组: 光合作用代谢调控机制研究组
杨文强,男,博士,研究员,博士生导师。

2000年和2003年在东北农业大学分别获学士和硕士学位,2008年在中国科学院遗传与发育生物学研究所获博士学位。20092月至20171月在美国斯坦福卡内基研究所植物生物学系从事博士后研究和研究助理工作。期间于2009年在美国科罗拉多再生能源国家实验室(NREL)访问研究。2017年入选"国家青年人才计划",20172月到中国科学院植物研究所工作,目前任中国科学院大学岗位教授、中科院光生物学重点实验室副主任、中国藻类学会理事、中国植物生理与植物分子生物学学会光合作用专业委员会委员、中国细胞生物学会青年工作委员会委员、中国细胞生物学会WLLA青年PI培训委员等职。担任The Plant Cell等多个国际期刊的审稿人。担任《热带作物学报》副主编、《土壤学报》编委、Frontier in Plant Science review editor。主要从事光合作用调控、叶绿体蛋白转运和质量控制以及豆科植物高光效相关研究。主持国家青年人才项目、基金委面上项目、科技部国家重点研发计划课题、中科院先导A项目子课题和任务等课题。在PNAS, Small Methods, Plant Cell, Plant J, Mol Plant, Plant Physiol, New Phytol等期刊发表论文30余篇,参编著作4本。荣获2021年中国科学院大学教学优秀奖。培养学生中多人次获得国家奖学金,毕业后出国深造、在国内大学、科研机构或者著名公司工作。

主要研究工作:

光合作用是地球上最大规模物质和能量转换的生物学过程,与人类生存息息相关。我们课题组以衣藻和豆科植物为研究对象,运用多学科理论与技术,研究以下内容:

1)光合作用调控机制。

揭示光合作用吸能、传能和转能过程中的机制,解析藻类二氧化碳识别、转运及浓缩机理,揭示与藻类 RuBisCO 酶活性高效的机理,揭示光合作用发生过程中的质量控制过程。

2)光合作用与碳代谢互作网络。

揭示碳代谢关键酶的功能,解析光合作用和碳代谢复杂网络之间的协同调控关系以及碳代谢对光合作用的反馈调控作用。

3)叶绿体蛋白转运与叶绿体质量控制。

揭示叶绿体蛋白转运、折叠及分拣和未折叠蛋白响应的分子机制,解析叶绿体质量控制过程中的自噬和叶绿体降解途径的调控机理及二者之间的关系。

4)大豆等豆科植物光合作用高光效机理。

挖掘豆科植物大豆、苜蓿等高光效的关键元件,解析高光效分子调控网络。

主持和参加的科研项目

[1] “微生物高效光合原件及模块的鉴定、功能表征及优化2020.01-2024.12),国家重点研发计划子课题,项目负责人。

[2] “创建生态草牧业科技体系项目”(2020.11-2025.10)中国科学院先导专项(A类)子课题,项目负责人。

[3] “种子精准设计的分子基础”(2019.11-2024.12)中国科学院先导专项(A类)子课题任务,项目负责人。

[4] “乙酸代谢在衣藻光合作用和黑暗异养中的作用机制研究2019.01-2022.12),国家自然科学基金面上项目,项目负责人。

[5] “从氧化还原平衡角度理解衣藻黑暗代谢和光合作用机制2018.01-2018.12),国家自然科学基金应急项目,项目负责人。

[6] “中组部人才计划启动基金2017.02-2022.02),项目负责人。

[7] “中国科学院人才计划启动基金2017.02-2020.02),项目负责人。

[8] “中国科学院植物研究所人才计划启动基金2017.02-2020.02),项目负责人。

研究论文(注*为通讯作者, §为共同第一作者):

2022

Xing J§, Pan J§, Yi H, Lv K, Gan Q, Wang M, Ge H, Huang X, Huang F, Wang Y, Rochaix J, Yang W*. 2022. The plastid-encoded protein Orf2971 is required for protein translocation and chloroplast quality control. The Plant Cell. doi: 10.1093/plcell/koac180.

Lv Y§, Han F§, Liu M§, Zhang T, Cui GS, Wang J, Yang Y, Yang Y, Yang W*. 2022. Characteristics of N6-methyladenosine modification during sexual reproduction of Chalmydomonas reinhardtii. Genom Proteom Bioinf. doi:10.1016/j.gpb.2022.04.004.

Li J, Yuan J, Li Y, Sun H, Ma T, Huai J, Yang W, Zhang W, Lin R*. 2022. The CDC48 complex mediates ubiquitin-dependent degradation of intra-chloroplast proteins in plants. Cell Rep. 39(2):110664.

Han C, Hua W, Li J, Qiao Y, Yao L, Hao W, Li R, Fan M, Jaeger GD, Yang W and Bai M*. 2022. TOR promotes guard cell starch degradation by regulating the activity of β-AMYLASE1 in Arabidopsis. The Plant Cell. doi: 10.1093/plcell/koab307.

2021

Gao Z§, Chen Z§, Cui Y§, Ke M§, Xu H, Xu Q, Chen J, Li Y, Huang L, Zhao H, Huang D, Mai S, Xu T, Liu X, Li S, Guan Y, Yang W, Friml J, Petrasek J, Zhang J, Chen X*. 2021. GmPIN-dependent polar auxin transport is involved in soybean nodule development. The Plant Cell. 33(9):2981-3003

2020

Wang Y§, Yang H§, Zhang X, Han F, Tu W* and Yang W*. 2020. Microalgal hydrogen production. Small Methods. 4: 1900514.

Tu W, Wu L, Zhang C, Sun R, Wang L, Yang W, Yang C and Liu C. 2020. Neoxanthin affects the stability of the C2S2M2-type photosystem II supercomplexes and the kinetics of state transition in Arabidopsis. Plant J. 104(6):1724-1735.

2019

Grossman AR, Luque ES, Yi H, Yang W*. 2019. Building the GreenCut2 suite of proteins to unmask photosynthetic function and regulation. Microbiology. 165:697-718.

Li Z, Mo W, Jia L, Xu Y, Tang W, Yang W, Guo Y, Lin R. 2019. Rice FLUORESCENT1 Is Involved in the regulation of chlorophyll. Plant Cell Physiol. 60(10):2307-2318

Liu J*, Sun Z, Mao X, Gerken H, Wang X, Yang W. 2019. Multiomics analysis reveals a distinct mechanism of oleaginousness in the emerging model alga Chromochloris zofingiensis. Plant J. doi: 10.1111/tpj.14302

2018

Wittkopp TM, Saroussi S, Yang W, Johnson X, Kim RG, Heinnickel ML, Russell JJ, Phuthong W, Dent RM, Broeckling CD, Peers G, Lohr M, Wollman FA, Niyogi KK, Grossman AR. 2018. GreenCut protein CPLD49 of Chlamydomonas reinhardtii associates with thylakoid membranes and is required for cytochrome b6 f complex accumulation. Plant J. 94(6):1023-1037

2016

Heinnickel M, Kim R, Wittkopp TM, Yang W, Walters K, Herbert S, Grossman AR. 2016. Tetratricopeptide repeat protein protects photosystem I from oxidative disruption during assembly. PNAS. pii: 201524040

2015

Yang W*§, Wittkopp TM§, Li X, Warakanont J, Dubini A, Catalanotti C, Kim RG, Nowack EC, Mackinder LC, Aksoy M, Page MD, D'Adamo S, Saroussi S, Heinnickel M, Johnson X, Richaud P, Alric J, Boehm M, Jonikas MC, Benning C, Merchant SS, Posewitz MC, Grossman AR. 2015. Critical role of Chlamydomonas reinhardtii ferredoxin-5 in maintaining membrane structure and dark metabolism. PNAS. 112(48): 14978-14983.

Yang W*, Catalanotti C, Wittkopp TM, Posewitz MC, Grossman AR. 2015. Algae after dark: mechanisms to cope with anoxic/Hypoxic conditions. Coming of age of Chlamydomonas as a model alga. Plant J 82(3):481-503.

2014

Yang W*, Catalanotti C, D'Adamo S, Wittkopp TM, Ingram-Smith CJ, Mackinder L, Miller TE, Heuberger AL, Peers G, Smith KS, Jonikas MC, Grossman AR, Posewitz MC. 2014. Alternative acetate production pathways in Chlamydomonas reinhardtii during dark anoxia and the dominant role of chloroplasts in fermentative acetate production. The Plant Cell. 26(11):4499-4518.

2013

Duanmu D, Rockwell NC, Dent RM, Niyogi KK, Yang W, Grossman AR, Lagarias C. 2013. Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival. PNAS.110(9):3621-6.

Catalanotti C, Yang W, Posewitz MC, Grossman AR. 2013. Fermentation metabolism and its evolution in algae. Front Plant Sci. doi: 10.3389/fpls.2013.00150.

Heinnickel ML, Alric J, Wittkopp T, Yang W, Catalanotti C, Dent RM, Niyogi KK, Wollman FA, Grossman AR. 2013. Novel thylakoid membrane greencut protein cpld38 impacts accumulation of the cytochrome b6f complex and associated regulatory processes. J Biol Chem. 288(10):7024-36.

2012

Catalanotti C, Dubini A, Subramanian V, Yang W, Magneschi L, Mus F, Seibert M, Posewitz MC, Grossman AR. 2012. Altered fermentative metabolism in Chlamydomonas reinhardtii mutants lacking pyruvate formate lyase and both pyruvate formate lyase and alcohol dehydrogenase. The Plant Cell. 24:692-707.

Magneschi L, Catalanotti C, Subramanian V, Dubini A, Yang W, Mus F, Posewitz MC, Seibert M, Perata P, Grossman AR. 2012. A mutant in the ADH1 gene of Chlamydomonas reinhardtii elicits metabolic restructuring during anaerobiosis. Plant Physiol. 158(3):1293-305.

2011

Meuser JE, D'Adamo S, Jinkerson RE, Mus F, Yang W, Ghirardi ML, Seibert M, Grossman AR, Posewitz MC. 2011. Genetic disruption of both Chlamydomonas reinhardtii [FeFe]-Hydrogenases: insight into the role of HYDA2 in H2 Production. Biochem Biophys Res Commun. 417(2):704-9.

Gonzalez-Ballester D, Pootakham W, Mus F, Yang W, Catalanotti C, Magneschi L, de Montaigu A, Higuera JJ, Prior M, Galván A, Fernandez E, Grossman AR. 2011. Reverse Genetics in Chlamydomonas: A moderate throughput platform for isolating insertional mutants. Plant Methods.7:24. doi:10.1186/1746-4811-7-24.

Grossman AR, Catalanotti C, Yang W, Dubini A, Magneschi L, Subramanian V, Posewitz MC, Seibert M. 2011. Multiple facets of anoxic metabolism and hydrogen production in the unicellular green alga Chlamydomonas reinhardtii. New Phytol. 190(2): 279-88.

2010及以前

Xu W, Yang R, Li M, Xing Z, Yang W, Chen G, Guo H, Gong X, Du Z, Zhang Z, Hu X, Wang D, Qian Q, Wang T, Su Z, Xue Y. 2010. Transcriptome analysis of diurnal genes in seedling and flag leaves of rice. PLoS One. 6(3): e17613

Yang W, Lai Y, Li M, Xu W, Xue Y. 2008. A Novel C2-domain-containing phospholipid binding protein, OsPBP1, is involved in pollen fertility in rice (Oryza sativa L.). Mol Plant. 1: 770-785

Yang W, Kong Z, Omo-Ikerodah E, Xu W, Li Q, Xue Y. 2008. A Calcineurin B-Like interacting protein kinase oscipk23 functions in pollination and drought stress responses in rice. J Genet Genomics.35:531-543

Li M, Xu W, Yang W, Kong Z, Xue Y. 2007. Genome-wide gene expression profiling reveals conserved and novel molecular functions of the stigma in rice (Oryza sativa L.). Plant Physiol.144:1797-1812

Kong Z, Li M, Yang W, Xu W, Xue Y, Xue Y. 2006. A novel nuclear-localized CCCH-type zinc finger protein, OsDOS, is involved in delaying leaf senescence in rice (Oryza sativa L.). Plant Physiol. 141: 1376–1388

专著:

2022

Xu Q, Liu X, Zhang C, Du W, Guan Y, Yang W* 2022. Insights into soybean With high photosynthetic efficiency. ELSEVIER: Advances in Botanical Research: Soybean Physiology and Genetics.

2021

Yang H, Han F, Wang Y, Yang W and Tu W* 2021. Strategies to study dark growth deficient or slower mutants in Chlamydomonas reinhardtii. Springer Nature: MiMB, Plant Photomorphogenesis.

2015

Wittkopp TM, Saroussi S, Yang W, Grossman AR. 2015. Chapter 11: The GreenCut - a tool for understanding the functions and relationships of proteins conserved in green lineage organisms. Horizon: Chloroplasts: Current Research and Applications.

2014

Yang W*, Catalanotti C, Posewitz MC, Alric J, Grossman AR. 2014. Insight into algal fermentation metabolism. Springer: Low Oxygen Stress in Plants.