姓 名: | 王文达 |
---|---|
职务/职称: | 研究员 |
联系电话: | (86)-010-62836729 |
电子邮件: | wdwang@ibcas.ac.cn |
个人网页: | http://www.klpbcas.com/yjzcy/hf_50082/ |
课 题 组: | 光合膜蛋白结构生物学研究组 |
王文达,男,博士,研究员。 |
2006年毕业于西南大学,2013年在中国科学院植物研究所取得博士学位并留所工作。 2016-2017年在日本冈山大学进行博士后研究,2020年1月晋升为研究员。主要从事植物和藻类光合作用研究,首次破解了硅藻光合膜蛋白超分子结构和功能之谜,揭示了植物环式电子传递调控能量平衡的新机制,为阐明硅藻捕获绿光和植物适应光环境的分子机理奠定了坚实基础,在已在Science, Nature, Nature communications, Advanced Science等发表论文40多篇。硅藻相关成果被Science特邀专题评为里程碑式的研究工作,入选2019年 “中国科学十大进展”、“中国生命科学十大进展”、“中国十大科技进展新闻”和“中国海洋十大进展”评选,入选国家“十三五”科技创新成就展。个人获中国植物生理与分子生物学学会卫志明青年创新奖、中国科学院第一届青年五四奖章等奖励。目前任植物所团委书记,兼任中国植物学会植物整合组学专业委员会秘书长,主持国自然优青基金、重点研发计划课题和中科院院创新交叉团队等项目。 主要研究方向: 主要研究方向为植物和藻类光合膜蛋白复合物结构、功能与调控机理研究。通过植物生理生化、分子生物学、结构生物学、人工智能和多组学等技术手段交叉研究光系统复合物、捕光天线、以及其他重要蛋白调控叶绿体发育和光合作用效率的分子机理。 主持和参加的科研项目: 国家自然科学基金优秀青年基金,2023-2025,主持 国家自然科学基金面上项目基金,2020-2023,主持 中国科学院青年创新促进会项目,2020-2023,主持 中国科学院创新交叉团队项目,2021-2023,主持 国家重点研发计划合成生物学专项青年科学家项目,2019-2024,参与 国家重点研发计划生物大分子与微生物组专项项目,2021-2026,参与,课题负责人 发表论文 (#标记为共同第一作者;*标记为通讯作者) 2023 (1) Yang Z#, Wang J#, Yin B, Liu W, Yin D, Shen J-R, Wang W*, Li L*, Guo X*. 2023. Stimuli-Induced Subconformation Transformation of the PSI-LHCI Protein at Single-Molecule Resolution. Advanced Science. 2205945. (2) Qiu S, Yuan Y, Li X, Zhao C, He Y, Tang B, Wang W, Fan J*.2023. Peridinin-chlorophyll-protein complex industry from algae: A critical review of the current advancements, hurdles, and biotechnological potential. Algal Research. 72: 103118. (3) Zhang S#, Tang K#, Yan Q#, Li X, Shen L, Wang W, He Y, Kuang T, Han G*, Shen JR*, Zhang X*.2023. Structural insights into a unique PSI-LHCI-LHCII-Lhcb9 supercomplex from moss Physcomitrium patens. Nature Plants. doi: 10.1038/s41477-023-01401-4. (4) Li DH, Wang W, Zhou C, Zhang Y, Zhao S, Zhou Y, Gao R, Yao H, Fu L, Wang P, Shen JR, Kuang T*, Zhang J*.2023. Photoinduced chlorophyll charge transfer state identified in the light-harvesting complex II from a marine green alga Bryopsis corticulans. iScience. 26, 105761. 2022 (5) Shen L#, Tang K#, Wang W#, Wang C, Wu H, Mao Z, An S, Chang S, Kuang T, Shen JR*, Han G*, Zhang X*.2022. Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare. Nature. 601:649-654. (6) Yao H-D, Li D-H, Gao R-Y, Zhou C, Wang W, Wang P, Shen JR, Kuang T*, Zhang JP*.2022. A Possible Mechanism for Aggregation-Induced Chlorophyll Fluorescence Quenching in Light-Harvesting Complex II from the Marine Green Alga Bryopsis corticulans. Journal of Physical Chemistry B. 126(46):9580-9590. (7) Zhu S, Bin S, Wang W, Lu S*, Yang W*.2022. Exogenous arachidonic acid affects fucoxanthin biosynthesis and photoprotection in Phaeodactylum tricornutum. Marine Drugs. 20 (10):644. 2021 (8) Wang J#, Yu LJ#, Wang W#, Yan Q, Kuang T, Qin X*, Shen JR*.2021. Structure of plant photosystem I‐light harvesting complex I supercomplex at 2.4 Å resolution. Journal of Integrative Plant Biology. 63(7):1367-1381. (9) Huang Z#, Shen L#, Wang W, Mao Z, Yi X, Kuang T, Shen J-R*, Zhang X*, Han G*.2021. Structure of photosystem I-LHCI-LHCII from the green alga Chlamydomonas reinhardtii in State 2. Nature Communications. 12:1100. (10) 赵松浩, 陶秋爽, 沈建仁, 王文达.2021. 硅藻岩藻黄素-叶绿素 a/c 蛋白-揭秘红系捕光天线复合物. 自然杂志. 43 : 157-164. (11) Huang G#, Xiao Y#, Pi X, Zhao L, Zhu Q, Wang W, Kuang T, Han G*, Sui SF*, Shen JR*.2021. Structural insights into a dimeric Psb27-photosystem II complex from a cyanobacterium Thermosynechococcus vulcanus. Proceeding of the National Academy of Sciences of USA. 118 (5): e2018053118. (12) Yan Q#, Zhao L#, Wang W, Pi X, Han G, Wang J, Cheng L, He YK, Kuang T, Qin X*, Sui SF*, Shen JR*.2021. Antenna arrangement and energy-transfer pathways of PSI–LHCI from the moss Physcomitrella patens. Cell Discovery. 7:10. 2020 (13) Chang L, Tian L, Ma F, Mao Z, Liu X, Han G, Wang W, Yang Y, Kuang T, Pan J, Shen JR.2020. Regulation of photosystem I-light-harvesting complex I from a red alga Cyanidioschyzon merolae in response to light intensities. Photosynthesis Research. 146:287-297. (14) Li D-H, Wang W, Zhou C, Zhang Y, Wang P, Shen J-R, Kuang T*, Zhang JP*.2020. Excitation Dynamics and Relaxation in the Major Antenna of a Marine Green Alga Bryopsis Corticulans. Biochimica et Biophysica Acta-Bioenergetics. 1861(5-6):148186. (15) Chen J-H, Wu H, Xu C, Liu X-C, Huang Z, Chang S, Wang W, Han G, Kuang T*,Shen JR*, Zhang X*.2020. Architecture of the photosynthetic complex from a green sulfur bacterium. Science. 370, eabb6350. (16) Zhu Q#, Yang Y#, Xiao Y, Wang W, Kuang T, Shen JR*, Han G*.2020. Function of PsbO-Asp158 in photosystem II: effects of mutation of this residue on the binding of PsbO and function of PSII in Thermosynechococcus vulcanus. Photosynthesis Research. 146:26-40. (17) Xiao Y, Zhu Q, Yang Y, Wang W, Kuang T, Shen JR*, Han G*.2020. Role of PsbV-Tyr137 in photosystem II studied by site-directed mutagenesis in the thermophilic cyanobacterium Thermosynechococcus vulcanus. Photosynthesis Research. 146:41–54. (18) Akhtar P, Nowakowski P J, Wang W, Do T N, Zhao S, Siligardi G, Garab G, Shen JR, Tan HS*, Lambrev PH*.2020. Spectral tuning of light-harvesting complex II in the siphonous alga Bryopsis corticulans and its effect on energy transfer dynamics. Biochimica et Biophysica Acta-Bioenergetics. 1861(5-6):148191. (19) Xu C#, Pi X#, HuangY#, Han G, Chen X, Qin X, Huang G, Zhao S, Yang Y , Kuang T, Wang W*, Sui S*, Shen JR*.2020. Structural basis for energy transfer in a huge diatom PSI-FCPI supercomplex. Nature Communications. 11:5081. (20) Wang W, Zhao S, Pi X, Kuang T, Sui SF, Shen JR.2020. Structural features of the diatom photosystem II–light-harvesting antenna complex. FEBS journal. 287(11):2191-2200. (21) 王文达, 韩广业, 匡廷云, 沈建仁.2020. 硅藻和绿藻:光合作用的蛋白体不再神秘. 前沿科学. 1, 14-18. 2019 (22) Wang W#, Yu LJ#, Xu C, Tomizaki T, Zhao S, Umena Y, Chen X, Qin X, Xin Y, Suga M, Han G, Kuang T*, Shen JR*.2019. Structural basis for blue-green light harvesting and energy dissipation in diatoms. Science. 363: eaav0365. (23) Pi X#, Zhao S#, Wang W#, Liu D, Xu C, Han G, Kuang T*, Sui SF*, Shen JR*.2019. The pigment-protein network of a diatom photosystem II-light harvesting antenna supercomplex. Science. 365: eaax4406. (24) Qin X#, Pi X#, Wang W, Han G, Zhu L, Liu M, Cheng L, Shen JR*, Kuang T*, Sui SF*.2019. Structure of a green algal PSI in complex with a large number of light-harvesting complex I subunits. Nature Plants. 5: 263-272. (25) Shen L#, Huang Z#, Chang S#, Wang W, Wang J, Kuang T, Han G*, Shen JR*, Zhang X*.2019. Structure of a C2S2M2N2-type PSII-LHCII supercomplex from the green alga Chlamydomonas reinhardtii. Proceeding of the National Academy of Sciences of USA. 116(42): 21246-21255. 2018 (26) Giovagnetti V, Han G, Ware M A, Ungerer P, Qin X, Wang W, Kuang T, Shen JR*, Ruban AV*.2018. A siphonous morphology affects light-harvesting modulation in the intertidal green macroalga Bryopsis corticulans (Ulvophyceae). Planta. 247:1293-1308. 2017 (27) Zhang T, Liu C, Dong W, Wang W, Sun Y, Chen X*, Yang C*, Dai N*.2017. Photoelectrochemical Complexes of Fucoxanthin-Chlorophyll Protein for Bio-Photovoltaic Conversion with a High Open-Circuit Photovoltage. Chemistry an Asian journal. 12: 2996-2999. (28) Tian L, Liu Z, Wang F, Shen L, Chen J, Chang L, Zhao S, Han G, Wang W, Kuang T, Qin X*, Shen JR*.2017. Isolation and characterization of PSI-LHCI super-complex and their sub-complexes from a red alga Cyanidioschyzon merolae. Photosynthesis research. 133: 201-214. 2016 (29) 徐才哲, 王文达, 艾鹏飞, 靳占忠, 桑 敏, 匡廷云.2016. 三角褐指藻岩藻黄素-叶绿素蛋白复合体的分离纯化和功能研究. 水生生物学报. 40 (1):109-115. (30) 李文军, 张超, 王文达, 赵松浩, 秦松.2016. 岩藻黄素与岩藻黄素-叶绿素复合体(FCP)研究进展. 食品研究与开发. 37 (23):191-196. 2015及以前 (31) 芦亚菲, 曲娜, 陈晓波, 王文达.2015. 对氢键网络的干扰降低细胞色素 b6f 复合体中Chla 的光稳定性. 中国科学: 生命科学. 45(3) :311 -316. (32) Feng J, Zhao S, Chen X, Wang W, Dong W, Chen J, Shen JR , Liu L*, Kuang T*.2015. Biochemical and structural study of Arabidopsis hexokinase 1, Aata Crystallographica Section D. Biological Crystallography. 71: 367-375. (33) Qin X#, Wang W#, Chang L, Chen J, Wang P, Zhang J, He Y, Kuang T*, Shen JR*.2015. Isolation and characterization of a PSI-LHCI super-complex and its sub-complexes from a siphonaceous marine green alga, Bryopsis Corticulans. Photosynthesis research. 123: 61-76. (34) Wang W#, Qin X#, Sang M, Chen D, Wang K, Lin R, Lu C, Shen JR*, Kuang T*.2013. Spectral and functional studies on siphonaxanthin-type lightharvesting complex of photosystem II from Bryopsis corticulans. Photosynthesis Research. 117: 267-279. (35) Qin X, Zhu J, Wang W, Ding X, Wang K, Fang Y*, Kuang T*.2013. A stable ‘sandwich’ system of Surface-Enhanced Resonance Raman Scattering for the analysis of β-carotenes in a photosynthetic pigment-protein complex. Journal of Raman Spectroscopy. 44: 1111-1119. (36) Sang M, Qin X, Wang W, Chen X, Xie J, Li L*, Kuang T*.2012. Singlet Oxygen Formation and Scavengingin Cytochrome b6f Complex from Spinach. ACTA BIOPHYSICA SINICA. 28(10): 848-854. (37) Sang M, Xie J, Qin X, Wang W, Chen X, Wang K, Zhang J*, Li L*, Kuang T. 2011. High-light induced superoxide radical formation in cytochrome b(6)f complex from Bryopsis corticulans as detected by EPR spectroscopy. Journal of photochemistry and photobiology B. 102: 177-181. (38) Sang M, Qin X, Wang W, Xie J, Chen X, Wang K, Zhang J, Li L*, Kuang T*.2011. High-light-induced superoxide anion radical formation in cytochrome b(6)f complex from spinach as detected by EPR spectroscopy. Photosynthetica. 49(1): 48-54. (39) Qin X#, Wang W#, Wang K, Xin Y, Kuang T*.2011. Isolation and characteristics of the PSI-LHCI-LHCII supercomplex under high light. Photochemistry and photobiology. 87: 143-150. (40) Sang M, Ma F, Xie J, Chen X, Wang K, Qin X, Wang W, Zhao J, Li L, Zhang J*, Kuang T*.2010. High-light induced singlet oxygen formation in cytochrome b(6)f complex from Bryopsis corticulans as detected by EPR spectroscopy. Biophysical chemistry. 146: 7-12. 著作: Wang W*, Shen JR*.2021. Chapter 6: Structure, Organization and Function of Light-Harvesting Complexes Associated with Photosystem II. Photosynthesis: Molecular Approaches to- Solar Energy Conversion, Springer, pp:163-194. 王文达, 沈建仁.2020. 硅藻光合膜蛋白超分子结构和功能之谜. 中国科协生命科学学会联合体编“中国生命科学十大进展2019”,中国科学技术出版社, 北京. pp:1-21. |